🔰Large-scale data integration | ArCHER

Large-scale data integration

Summary

This project aims to develop new tools and applications for biological data integration.

Development of a web-based search engine to assist biomedical research and drug discovery
RDFization of data from NIBIO databases (such as Open TG-GATEs)
Catalogueing biomedical databases in Japan

Funding

Recent achievements

Web-based Search Engine, Sagace.

Collaborators

Software ＆ Database

Publications

2012

Morita, M., Igarashi, Y., Ito, M., Chen, Y.-A., Nagao, C., Sakaguchi, Y., Sakate, R., Masui, T., & Mizuguchi, K. 2012 Sagace: A web-based search engine for biomedical databases in Japan. BMC Research Notes 5(1), 604 doi

Another ongoing projects (research)

Biomarker discovery and toxicity prediction

Development of a pharmacokinetics database and prediction models

An Integrated Platform for Toxicogenomics Data Analysis

The Adjuvant Database Project

New therapeutic strategies based on molecular mechanisms

Development of in silico screening methods

Prediction of protein-protein interactions

An application to breast cancer therapies

Enzyme structures and functions

Discovery of drug targets

Development of AI for discovery of drug targets

Development of databases for prioritization and evaluation of novel drug targets

Other projects

Investigating the relationships between gut microbiota and life style: the deve…

Large-scale data integration (in collaboration with the NBDC)

Finished projects

Development of an international pharmaceutical innovation value chain for in si…

Development of a novel method for modelling dynamic structures of membrane prot…

High throughput algorithms for predicting specificity in regulatory interactions

SW & DB

Details

News

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2024-10-16
"A modern multi-omics data exploration experience with Panomicon" has been published.
Bioinformatics P.database bioinformatics drug discovery研究論文
2024-08-09
"Construction of a <i>T</i>m-value prediction model and molecular dynamics study of AmNA-containing gapmer antisense oligonucleotide" has been published.
Bioinformatics P.molecular simulation drug discovery machine learning研究論文
2024-01-25
"Ramen Consumption and Gut Microbiota Diversity in Japanese Women: Cross-Sectional Data from the NEXIS Cohort Study" has been published.
Guest researchers in Silico P.microbiome研究論文
2024-01-25
"DruMAP: A Novel Drug Metabolism and Pharmacokinetics Analysis Platform" has been published.
Guest researchers in Silico P.drug discovery machine learning研究論文
2024-01-25
"Changes in Fecal Gut Microbiome of Home Healthcare Patients with Disabilities through Consumption of Malted Rice Amazake" has been published.
Guest researchers in Silico P.microbiome研究論文

Presentations

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2023-10-11
Senior Research Scientist, Mari N. Itoh give poster presentation at [ERS2023].
Bioinformatics P.poster
2023-10-10
Suyong Re give an invited lecture at [Molcube 2023 Mini-Symposium].
in Silico P.molecular simulationtalk
2022-11-08
Postdoctoral Fellow, Attayeb Mohsen will give poster presentation at [IHMC2022].
AI Nutrition P.in Silico P.Toxicogenomics P.Bioinformatics P.microbiomeposter
2022-09-18
Postdoctoral Fellow, Rodolfo Sebastian Allendes Osorio will give poster presentation at [ECCB2022].
AI Nutrition P.in Silico P.Toxicogenomics P.Bioinformatics P.poster
2022-09-18
Project Leader, Yayoi Natsume will give poster presentation at [ECCB2022].
Bioinformatics P.presentation