We carry out bioinformatics and computational biology research into drug discovery and development (with special emphasis on early-stage target discovery and toxicity prediction). Our research involves both the analysis of real-life experimental data and the development of novel computational techniques, aiming to establish systems approaches to drug discovery.
Our current research projects include:
Analysis of large-scale experimental data and the development of integrated databases for target discovery and safety prediction
Prediction of protein-protein or protein-small molecule interactions, modelling of their impact on phenotypic responses and applications to drug design.
"Construction of a <i>T</i>m-value prediction model and molecular dynamics study of AmNA-containing gapmer antisense oligonucleotide" has been published.